Urology Today.net

Site updated at Thursday, 12 May 2016

Common Urological Problems

Turner Syndrome

Genetic basis of genitourinary malformations

A working knowledge of the embryology of the genitourinary tract provides the basis for understanding the structural anomalies encountered in paediatric urological practice. Although this section will concentrate predominantly on the clinical aspects of embryology of the genitourinary tract it will also touch on some of the relevant basic science   and   summarise… Genetic basis of genitourinary malformations   



Embryogenesis -Paediatric Urology

Human gestation spans a period of 38 weeks, from fertilisation to birth. Conventionally, pregnancy is divided into three trimesters,  each of 3 months’ duration.  The formation of organs and systems (embryogenesis)  takes place principally between the third and 10th weeks of gestation. Throughout the remainder, the fetal organs undergo differentiation, branching, maturation and growth.… Embryogenesis -Paediatric Urology   



Genital tracts

The internal and external genitalia of both sexes are genetically ‘programmed’ to differentiate passively down a ‘default’  female pathway unless actively switched down a male pathway by the genetic information carried by the testis-determining gene (SRY).  Until the sixth week of gestation,  the genitalia of both sexes share identical embryonic precursors.  Differentiation   of… Genital tracts   



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