Urology Today.net

Site updated at Thursday, 12 May 2016

Common Urological Problems

Nephropathy

IgA Nephropathy

Primary   hematuria   (idiopathic   benign   and   recurrent hematuria,  Berger’s disease)  is now known to be an immune complex glomerulopathy in which deposition of IgA occurs in a granular pattern in the mesangium of the glomerulus.  The associated light microscope findings are variable and range from normal to extensive crescentic glomerulonephritis.… IgA Nephropathy   



Clinical Findings in Nephrosis

A. SYMPTOMS AND SIGNS
Edema may appear insidiously and increase slowly or can appear suddenly and accumulate rapidly. Symptoms other than those related to the mechanical effects of edema are not remarkable.

On physical examination, massive peripheral edema is apparent.  Signs of hydrothorax and ascites are common.

Pallor is often accentuated… Clinical Findings in Nephrosis   



NIH study finds genetic clues to major cause of kidney disease worldwide

For the first time, researchers have found five regions in the human genome that increase susceptibility to immunoglobulin A (IgA) nephropathy, a major cause of kidney failure worldwide — systematically identifying those that point to a tendency for IgA nephropathy, or a protection against it.

“The study is unique in identifying the biological pathways… NIH study finds genetic clues to major cause of kidney disease worldwide   



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