Urology Today.net

Site updated at Thursday, 12 May 2016

Common Urological Problems

Psa

Prostate cancer screening may help healthy men only

Screening men for prostate cancer makes sense only if they are generally healthy, U.S. researchers said on Monday.

They found that even if screening doesn’t help men live longer overall—as shown by a large U.S. study last year—it’s possible that some may still benefit.

Today, doctors commonly screen men over 50 for prostate cancer… Prostate cancer screening may help healthy men only   



Study Seeks Volunteers with Prostate Cancer to Measure Safety of Robotic Stereotactic Radiosurgery

The North Shore-LIJ Health System Department of Radiation Medicine announced today it is seeking patients with early-stage (confined to the organ) prostate cancer to participate in a Phase I Research study.

Subjects must be newly diagnosed and considered lower risk, with a Gleason score of equal to or less than 7 and a PSA… Study Seeks Volunteers with Prostate Cancer to Measure Safety of Robotic Stereotactic Radiosurgery   



Doctors Issue New Guidelines on Spotting, Treating Enlarged Prostate

Experts at the American Urological Association (AUA) have issued updated guidelines on diagnosing and treating enlarged prostate—a common condition formally know as benign prostatic hyperplasia (BPH).

BPH can lead to lower urinary tract symptoms such as incontinence and affect a man’s quality of life. The new guidelines, the first since 2003, include a detailed… Doctors Issue New Guidelines on Spotting, Treating Enlarged Prostate   



PSA velocity screening for prostate cancer may lead to unnecessary biopsies

Guidelines of several cancer organizations have recommended that men with a rapid rise in PSA have a biopsy for prostate cancer, even if there is no other indication and the PSA is within the “normal” range. But change in PSA - known as PSA velocity - is a poor predictor of prostate cancer, and… PSA velocity screening for prostate cancer may lead to unnecessary biopsies   



MRI locates prostate cancer recurrence at extremely low PSA levels

A pelvic MRI scan with IV contrast and rectal balloon is highly effective in identifying local recurrence even at low PSA values in prostate cancer patients with a rising or persistently elevated PSA after prostatectomy, according to a study presented April 29, 2011, at the Cancer Imaging and Radiation Therapy Symposium in Atlanta. The… MRI locates prostate cancer recurrence at extremely low PSA levels   



Antifungal drug delays need for chemo in advanced prostate cancer

The oral antifungal drug itraconazole, most commonly used to treat nail fungus, may keep prostate cancer from worsening and delay the need for chemotherapy in men with advanced disease. Details of the finding, from a clinical trial led by Johns Hopkins experts, are scheduled for presentation on Saturday, June 4 at the 2011 American… Antifungal drug delays need for chemo in advanced prostate cancer   



National study finds vitamin E supplement may increase prostate cancer risk

Cleveland: Men who take a daily vitamin E supplement - a regimen once thought to reduce cancer risk – face an increased risk of prostate cancer, according to results of a large national study.

The finding comes from a report summarizing the latest results of the Selenium and Vitamin E Cancer Prevention Trial (SELECT).… National study finds vitamin E supplement may increase prostate cancer risk   



Age a Big Factor in Prostate Cancer Deaths

Contrary to common belief, men age 75 and older are diagnosed with late-stage and more aggressive prostate cancer and thus die from the disease more often than younger men, according to a University of Rochester analysis published online this week by the journal, Cancer.

The study is particularly relevant in light of the recent… Age a Big Factor in Prostate Cancer Deaths   



Biopsy referral after PSA screening stays consistent over time

After the US Prostate Cancer Prevention Trial found cancer in many men with low levels of prostate specific antigen (PSA), many debated which PSA level should lead to a biopsy recommendation. The US Preventive Screening Task Force (USPSTF) recently concluded, amid considerable controversy, that the evidence does not support recommending PSA screening for men… Biopsy referral after PSA screening stays consistent over time   



Prostate Cancer Study Proves Drug Delays Disease Progression

For men diagnosed with low-risk, localized prostate cancer, being treated with the drug dutasteride (“Avodart”) delays disease progression and initiating active treatment, and also reduces anxiety, show the results of a three-year international clinical trial led by Dr. Neil Fleshner, Head of the Division of Urology, University Health Network (UHN).

The findings are published… Prostate Cancer Study Proves Drug Delays Disease Progression   



A new screening method for prostate cancer

A new study by NYU Langone Medical Center and Northwestern University Feinberg School of Medicine shows novel PSA velocity (PSAV) risk count testing may provide a more effective way for physicians to screen men for clinically significant prostate cancer. The new study, published online by the British Journal of Urology International on February 1,… A new screening method for prostate cancer   



In prostate cancer, other death risks may be higher

Some men with prostate cancer may have increased risks of dying from causes other than the cancer itself, a new study finds.

Researchers found that when men had their prostate cancer diagnosed after developing symptoms - and not after screening tests - they had heightened risks of dying from heart problems or other cancers.… In prostate cancer, other death risks may be higher   



Novel Technology Allows for Noninvasive Imaging of Prostate Cancer

Use of a novel, noninvasive imaging tool allowed researchers to measure free prostate-specific antigen in prostate cancer models and to visualize bone metastasis in a tumor-specific manner, according to results published in Cancer Discovery, a journal of the American Association for Cancer Research.

Results of this paper were presented here at an AACR Annual… Novel Technology Allows for Noninvasive Imaging of Prostate Cancer   



PSA Drop Seen with New Prostate Cancer Drug

Half of a group of men with castration-resistant prostate cancer (CRPC) had biochemical responses to treatment with an investigational androgen receptor modulator, data from a preliminary clinical study showed.

During 12 weeks of treatment with galeterone, prostate-specific antigen (PSA) declined by at least 30% in 24 of 49 patients, 11 of whom had declines… PSA Drop Seen with New Prostate Cancer Drug   



Antifungal May Help in Prostate Cancer

Men with castration-resistant prostate cancer (CRPC) that was not mediated by androgen suppression experienced better outcomes when treated with an antifungal agent, according to a small clinical study reported here.

Men treated with the maximum recommended dose of itraconazole had a median progression-free survival (PFS) of 36 weeks, and 61% of the patients were… Antifungal May Help in Prostate Cancer   



Prostate Cancer: Men Should Skip Common Blood Test, Panel Says

Men should not be screened for prostate cancer with a common blood test, a widely followed federal advisory panel recommended Monday.

But the report is not likely to quell a dispute about whether the test’s risks outweigh its potential benefits.

The US Preventive Services Task Force recommended a “D” grade for prostate-specific-antigen, or PSA,… Prostate Cancer: Men Should Skip Common Blood Test, Panel Says   



Some docs screen for prostate cancer without asking

One in four family doctors doesn’t ask male patients before screening them for prostate cancer, according to a new survey.

So-called prostate specific antigen (PSA) testing has been controversial in recent years because of uncertainty about whether it actually saves lives and concern about side effects from potentially unnecessary and invasive follow-up tests and… Some docs screen for prostate cancer without asking   



PSA decision tools may help men clarify their values

Giving men decision-making tools to help them consider the pros and cons of prostate cancer screening changed how they valued different possible outcomes but did not affect how many chose to be tested, in a new study.

A report last month suggested that one in four family doctors regularly screens men for prostate cancer… PSA decision tools may help men clarify their values   



Chronic inflammation may be linked to aggressive prostate cancer

The presence of chronic inflammation in benign prostate tissue was associated with high-grade, or aggressive, prostate cancer, and this association was found even in those with low prostate-specific antigen (PSA) levels, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

An analysis of… Chronic inflammation may be linked to aggressive prostate cancer   



Electronic nose sniffs out prostate cancer using urine samples

We may soon be able to make easy and early diagnoses of prostate cancer by smell. Investigators in Finland have established that a novel noninvasive technique can detect prostate cancer using an electronic nose. In a proof of principle study, the eNose successfully discriminated between prostate cancer and benign prostatic hyperplasia (BPH) by “sniffing”… Electronic nose sniffs out prostate cancer using urine samples   



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