Urology Today.net

Site updated at Thursday, 12 May 2016

Common Urological Problems

Prostate Specific Antigen

Prostate cancer screening may help healthy men only

Screening men for prostate cancer makes sense only if they are generally healthy, U.S. researchers said on Monday.

They found that even if screening doesn’t help men live longer overall—as shown by a large U.S. study last year—it’s possible that some may still benefit.

Today, doctors commonly screen men over 50 for prostate cancer… Prostate cancer screening may help healthy men only   



Doctors Issue New Guidelines on Spotting, Treating Enlarged Prostate

Experts at the American Urological Association (AUA) have issued updated guidelines on diagnosing and treating enlarged prostate—a common condition formally know as benign prostatic hyperplasia (BPH).

BPH can lead to lower urinary tract symptoms such as incontinence and affect a man’s quality of life. The new guidelines, the first since 2003, include a detailed… Doctors Issue New Guidelines on Spotting, Treating Enlarged Prostate   



Age a Big Factor in Prostate Cancer Deaths

Contrary to common belief, men age 75 and older are diagnosed with late-stage and more aggressive prostate cancer and thus die from the disease more often than younger men, according to a University of Rochester analysis published online this week by the journal, Cancer.

The study is particularly relevant in light of the recent… Age a Big Factor in Prostate Cancer Deaths   



Some men can delay prostate cancer treatment: panel

Men with low-risk prostate cancer may wait to see if their disease progresses before treating it, an independent panel of experts convened by the U.S. National Institutes of Health (NIH) said on Wednesday.

The panel backed the so-called active monitoring approach to prostate cancer treatment as a way to help men avoid the potential… Some men can delay prostate cancer treatment: panel   



Prostate Cancer Study Proves Drug Delays Disease Progression

For men diagnosed with low-risk, localized prostate cancer, being treated with the drug dutasteride (“Avodart”) delays disease progression and initiating active treatment, and also reduces anxiety, show the results of a three-year international clinical trial led by Dr. Neil Fleshner, Head of the Division of Urology, University Health Network (UHN).

The findings are published… Prostate Cancer Study Proves Drug Delays Disease Progression   



Novel Technology Allows for Noninvasive Imaging of Prostate Cancer

Use of a novel, noninvasive imaging tool allowed researchers to measure free prostate-specific antigen in prostate cancer models and to visualize bone metastasis in a tumor-specific manner, according to results published in Cancer Discovery, a journal of the American Association for Cancer Research.

Results of this paper were presented here at an AACR Annual… Novel Technology Allows for Noninvasive Imaging of Prostate Cancer   



PSA Drop Seen with New Prostate Cancer Drug

Half of a group of men with castration-resistant prostate cancer (CRPC) had biochemical responses to treatment with an investigational androgen receptor modulator, data from a preliminary clinical study showed.

During 12 weeks of treatment with galeterone, prostate-specific antigen (PSA) declined by at least 30% in 24 of 49 patients, 11 of whom had declines… PSA Drop Seen with New Prostate Cancer Drug   



Antifungal May Help in Prostate Cancer

Men with castration-resistant prostate cancer (CRPC) that was not mediated by androgen suppression experienced better outcomes when treated with an antifungal agent, according to a small clinical study reported here.

Men treated with the maximum recommended dose of itraconazole had a median progression-free survival (PFS) of 36 weeks, and 61% of the patients were… Antifungal May Help in Prostate Cancer   



PSA decision tools may help men clarify their values

Giving men decision-making tools to help them consider the pros and cons of prostate cancer screening changed how they valued different possible outcomes but did not affect how many chose to be tested, in a new study.

A report last month suggested that one in four family doctors regularly screens men for prostate cancer… PSA decision tools may help men clarify their values   



Urologists echo call for discussion before PSA test

Urologists fell in line with other doctor groups on Friday in recommending careful consideration and discussion when it comes to screening for prostate cancer, rather than a gung-ho approach.

At its annual meeting in San Diego, California, the American Urological Association (AUA) recommended against screening average-risk men under age 55 or any man over… Urologists echo call for discussion before PSA test   



Chronic inflammation may be linked to aggressive prostate cancer

The presence of chronic inflammation in benign prostate tissue was associated with high-grade, or aggressive, prostate cancer, and this association was found even in those with low prostate-specific antigen (PSA) levels, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

An analysis of… Chronic inflammation may be linked to aggressive prostate cancer   



Low risk prostate cancer not always low risk

More and more men who believe they have low-risk prostate cancers are opting for active surveillance, forgoing treatment and monitoring the cancer closely with prostate-specific antigen (PSA) tests, digital rectal exams and ultrasounds at regular intervals to see if their tumors are growing. Nearly 400 men are now enrolled in the UCLA Active Surveillance… Low risk prostate cancer not always low risk   



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