Urology Today.net

Site updated at Thursday, 12 May 2016

Common Urological Problems

Kidney Transplant

A new target in polycystic kidney disease

In work suggesting a new approach to treating polycystic kidney disease (PKD), a leading cause of kidney failure, researchers at Children’s Hospital Boston were able to block the formation of fluid-filled cysts, the hallmark of the disease, in a mouse model. Their findings, using a compound that inhibits a receptor known as c-Met, will… A new target in polycystic kidney disease   



Jefferson Offers Adult Kidney Transplant Patients the Lowest Wait Times in City, Per National Databa

A recent listing* of Philadelphia adult kidney transplant programs by The Scientific Registry of Transplant Recipients (SRTR) has listed the transplant program at Thomas Jefferson University Hospital as having the shortest wait times for patients seeking a transplant among programs that have a three-year survival rate of greater than 90 percent. The median wait… Jefferson Offers Adult Kidney Transplant Patients the Lowest Wait Times in City, Per National Databa   



Kidney Transplant Recipients: Get Moving to Save Your Life

Low physical activity increases kidney transplant patients’ likelihood of dying early, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The results suggest that patients need to exercise to fend off an early death.

Inactive people in general face increased risks of developing cardiovascular… Kidney Transplant Recipients: Get Moving to Save Your Life   



Gene Variant Influences Chronic Kidney Disease Risk

A team of researchers from the United States and Europe has identified a single genetic mutation in the CUBN gene that is associated with albuminuria both with and without diabetes. Albuminuria is a condition caused by the leaking of the protein albumin into the urine, which is an indication of kidney disease.

The research… Gene Variant Influences Chronic Kidney Disease Risk   



Survival Matching Should be Used to Allocate Kidneys to Transplant Recipients

Providing kidney transplants to patients with the best probability of longer survival would reduce repeat transplant operations and improve life span after kidney transplant, says a U-M researcher in a commentary published in the New England Journal of Medicine March 16.

Alan B. Leichtman, M.D., professor of Internal Medicine at U-M and his co-authors… Survival Matching Should be Used to Allocate Kidneys to Transplant Recipients   



UCSB Scientists Discover New Drug Target for Kidney Disease

Two discoveries at UC Santa Barbara point to potential new drug therapies for patients with kidney disease. The findings are published in this week’s issue of the Proceedings of the National Academy of Sciences.

Over 600,000 people in the U.S., and 12 million worldwide, are affected by the inherited kidney disease known as autosomal-dominant… UCSB Scientists Discover New Drug Target for Kidney Disease   



Aboriginal children less likely to receive kidney transplants

Aboriginal children with kidney failure were less likely to receive a kidney transplant compared to white children, found an article in CMAJ (Canadian Medical Association Journal) (pre-embargo link only).

Compared with non-Aboriginal people, Aboriginal adults with kidney failure in Canada have lower rates of kidney transplantation, the best treatment for kidney failure.… Aboriginal children less likely to receive kidney transplants   



Continued Treatment for Lupus May Boost Survival of Those Patients with End-Stage Kidney Disease

Researchers at Albert Einstein College of Medicine of Yeshiva University have shown that close supervision by rheumatologists and the use of immunosuppressant drugs improve the survival of lupus patients with end-stage kidney disease - a finding that could reverse long-standing clinical practice. Their study appeared in the September 1 online edition of the Journal… Continued Treatment for Lupus May Boost Survival of Those Patients with End-Stage Kidney Disease   



Never Too Old to Donate a Kidney?

People over age 70 years of age can safely donate a kidney, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The results provide good news for patients who need a kidney but have limited options for donors; however, kidneys from these elderly donors… Never Too Old to Donate a Kidney?   



Racial inequalities exist for kids with kidney disease

Among children with kidney disease, certain races are less likely to get kidney transplants and are more likely to die than other races, according to two studies from Emory University that were presented during the American Society of Nephrology’s Annual Kidney Week.

Kidney transplantation is the optimal treatment for patients with kidney failure, but… Racial inequalities exist for kids with kidney disease   



Are Some Patients Too Heavy for a New Kidney?

In a research review article published in the American Journal of Nephrology, Saint Louis University investigators examined data from multiple studies to better understand how obesity, an epidemic in the U.S., impacts kidney transplant patients. The authors report that, even as some connections between weight and health outcomes are unknown or contradictory, there… Are Some Patients Too Heavy for a New Kidney?   



Low vitamin D linked with lower kidney function after transplantation

Vitamin D deficiency may decrease kidney function in transplant recipients, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The finding suggests that vitamin D supplementation may help improve the health of kidney transplant recipients.

Vitamin D deficiency is prevalent in patients with kidney… Low vitamin D linked with lower kidney function after transplantation   



Urine test can diagnose, predict kidney transplant rejection

Analysis of three biomarkers in the urine of kidney transplant recipients can diagnose - and even predict - transplant rejection, according to results from a clinical trial sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. This test for biomarkers - molecules that indicate the… Urine test can diagnose, predict kidney transplant rejection   



Obese kidney failure patients receive survival benefit from transplantation

Most obese individuals with kidney failure can prolong their lives by receiving a kidney transplant, although this survival benefit is lower in severely obese individuals. That’s the conclusion of a new study published in the American Journal of Transplantation. The findings will hopefully decrease differences in access to transplantation for obese patients.

Obesity is… Obese kidney failure patients receive survival benefit from transplantation   



‘Big data’ technique improves monitoring of kidney transplant patients

A new data analysis technique radically improves monitoring of kidney patients, according to a University of Leeds-led study, and could lead to profound changes in the way we understand our health.

The research, published in the journal PLoS Computational Biology, provides a way of making sense out of the huge number of clues about… ‘Big data’ technique improves monitoring of kidney transplant patients   



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