Urology Today.net

Site updated at Thursday, 12 May 2016

Common Urological Problems

Kidney Cancer

Research provides new kidney cancer clues

Researchers have identified a gene that is mutated in one in three patients with the most common form of renal cancer. The identification of a frequently mutated gene will provide new insights into the biology of the disease. This biological knowledge will be critical in the continued effort to improve treatment for renal cancer.… Research provides new kidney cancer clues   



Kidney cancer linked to mutated gene

A mutated gene has been found in a third of patients with the most common form of kidney cancer.

The researchers said the discovery of a second major gene linked to renal cancer was a major advance.

The study, published in the journal Nature, shows the gene is involved in packaging DNA in the… Kidney cancer linked to mutated gene   



Kidney cancer discovery could expand treatment options

Oregon Health & Science University Knight Cancer Institute researchers uncovered a gene that may be the key to helping kidney cancer patients who don’t respond to current therapies. This discovery could also provide a toolkit to identify patients who are most likely to benefit from drugs that block this gene from causing cancer cells… Kidney cancer discovery could expand treatment options   



Lymphocyte count indicates the prognosis of patients with renal cell carcinoma

Each year, kidney cancer is diagnosed in nearly 60,000 people in the U.S. Many of these patients undergo surgery to remove the affected kidney, but this procedure can be risky for the elderly and those who have other health problems. Unfortunately, the prognosis of kidney cancer patients often cannot be determined until tumor samples… Lymphocyte count indicates the prognosis of patients with renal cell carcinoma   



FDA panel backs Pfizer’s drug for kidney cancer

Pfizer Inc won unanimous expert backing for its Inlyta experimental drug for patients with advanced kidney cancer.

A Food and Drug Administration advisory committee voted 13-0 on Wednesday that the drug, also called axitinib, had a favorable benefit-risk profile for such patients after initial treatment has failed.

The FDA, which usually approves products that… FDA panel backs Pfizer’s drug for kidney cancer   



Two Recent Studies Distinguish Kidney Cancer Subtypes And Provide Promising New Drug Targets

Two recent studies by Van Andel Research Institute scientists are providing a foundation for a more complete understanding of distinct kidney cancer subtypes, which could pave the way for better treatments.

In a study published in Cancer Cell led by Kyle Furge, Ph.D. and Aikseng Ooi, Ph.D., researchers provide a more complete understanding of… Two Recent Studies Distinguish Kidney Cancer Subtypes And Provide Promising New Drug Targets   



Robot-Assisted Surgery Now Favored Treatment for Kidney Cancer

Robot-assisted surgery has replaced another minimally invasive operation as the main procedure to treat kidney cancer while sparing part of the diseased organ, and with comparable results, according to a new research study by Henry Ford Hospital urologists.

While the study shows that robot-assisted partial nephrectomy (RAPD), available only since 2004, may also offer… Robot-Assisted Surgery Now Favored Treatment for Kidney Cancer   



Active surveillance provides a viable alternative to surgery for small kidney masses

Active surveillance of small kidney masses is a safe and effective alternative to immediate surgery, with similar overall and cancer specific survival rates, according to a study published in the November issue of the urology journal BJUI.

The technique is primarily used to treat elderly patients who have complex health issues or decline surgery.… Active surveillance provides a viable alternative to surgery for small kidney masses   



Dartmouth researchers test safety of Nivolumab in kidney cancer

Researchers at Dartmouth-Hitchcock Norris Cotton Cancer Center will present a poster on a phase I clinical trial of Nivolumab, a PD-1 receptor blocking antibody, being used in combination with other drugs in patients with metastatic renal cell carcinoma (mRCC) at the ASCO Annual Meeting on June 3, 2013.

Metastatic renal cell carcinoma or kidney… Dartmouth researchers test safety of Nivolumab in kidney cancer   



Low cholesterol linked with worse survival in patients with kidney cancer

People are often told to reduce their cholesterol to improve their heart health, but new research suggests that low cholesterol may increase kidney cancer patients’ risk of dying from their disease. The findings, which are published in BJU International, indicate that cholesterol testing may help doctors as they monitor and treat patients with kidney… Low cholesterol linked with worse survival in patients with kidney cancer   



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