Urology Today.net

Site updated at Thursday, 12 May 2016

Common Urological Problems

Diabetic Nephropathy

Clinical Findings in Nephrosis

A. SYMPTOMS AND SIGNS
Edema may appear insidiously and increase slowly or can appear suddenly and accumulate rapidly. Symptoms other than those related to the mechanical effects of edema are not remarkable.

On physical examination, massive peripheral edema is apparent.  Signs of hydrothorax and ascites are common.

Pallor is often accentuated… Clinical Findings in Nephrosis   



Scientists learn more about how kidneys fail and how new drugs may intervene

Scientists are learning more about how protein gets in the urine when the kidneys begin to fail and how a new drug blocks it.

“We have known for a long time that renal failure comes with protein in your urine, especially in diabetes,” said Dr. David Pollock, renal physiologist at the Medical College of… Scientists learn more about how kidneys fail and how new drugs may intervene   



Protein offers new clue to cause and treatment for kidney disease

University of Alabama at Birmingham researchers have pinpointed a protein that compromises the kidney’s filtering ability, causing nephrotic syndrome, and demonstrated that a naturally occurring precursor of an acid in the body offers potential for treating some forms of the condition.

The research was published online Dec. 12 in Nature Medicine.

“This is a… Protein offers new clue to cause and treatment for kidney disease   



Low Carbohydrate Diet May Reverse Kidney Failure in People with Diabetes

Researchers from Mount Sinai School of Medicine have for the first time determined that the ketogenic diet, a specialized high-fat, low carbohydrate diet, may reverse impaired kidney function in people with Type 1 and Type 2 diabetes. They also identified a previously unreported panel of genes associated with diabetes-related kidney failure, whose expression was… Low Carbohydrate Diet May Reverse Kidney Failure in People with Diabetes   



TGen findings contribute to understanding of diabetic kidney disease

A gene called PVT1 may help reduce the kidneys ability to filter blood, leading to kidney disease, kidney failure and death, according to a study published today by researchers at the Translational Genomics Research Institute (TGen).

The TGen team found PVT1 expression levels increased up to 5-fold in response to hyperglycemia, or high blood… TGen findings contribute to understanding of diabetic kidney disease   



Research aims to prevent diabetic kidney failure

The enzyme arginase-2 plays a major role in kidney failure, and blocking the action of this enzyme might lead to protection against renal disease in diabetes, according to researchers.

“We believe these arginase inhibitors may be one of the new targets that can slow down the progression of, or even prevent the development of,… Research aims to prevent diabetic kidney failure   



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